1. Use Built-in Functions and Libraries

2. Avoid Global Variables

3. Use Generators

4. Use Set and Dictionary Comprehension  

5. Use the most efficient data structure for the task

6. Use decorators to simplify your code

7. Use the join method for joining strings

8. Avoid using try-except blocks when possible

9. Use the Python debugger (pdb) to optimize your code  

10. Use Cython to speed up your code